Clinical research
Institutional clinical trials supported by the Centre of Evidence of the French Society of Dermatology 
| Project | Principal Investigator | President of Scientific Committee/SFD thematic groups involved | Sponsor | Description | Funding | Status | ClinicalTrials.gov number |
| GALE-SCRATCH | Franck BORALEVI | Olivier CHOSIDOW / SFDP, GrIDIST, CDP | Bordeaux University Hospital | Randomised controlled trial comparing the efficacy of 2-dose oral ivermectin versus 5% permethrin to treat scabies in children and adults: SCRATCH trial (SCabies Randomised Trial in CHildren) | PHRC National 2011 | Published: Download | NCT02407782 |
| GALE-CRUSTED | Giao DO-PHAM | Olivier CHOSIDOW / GrIDIST, CDP | AP-HP | Randomised, double-blind, controlled trial evaluating the efficacy of ivermectin 400 µg versus ivermectin 200 µg/kg in severe scabies. GALE-CRUSTED trial. | PHRC National 2014 | Accepted in the NEJM | NCT02841215 |
| SHAREII | Tu-Anh DUONG | Olivier CHOSIDOW / GrIDIST, CDP | AP-HP | Non-inferiority randomized clinical trial comparing a short course of oral amoxicillin vs. standard 10-day treatment for leg erysipelas – SHARE II Study (Short course of Amoxicillin for Erysipelas) | PHRC National 2015 | The sites are open; the inclusions will start | NCT07104552 |
| CONDYVAC | Sébastien FOUERE | Olivier CHOSIDOW/ GrIDIST, CDP | AP-HP | Efficacy of Quadrivalent HPV Vaccine to Prevent Relapses of Genital Warts After Initial Therapeutic Response | PHRC National 2015 | Inclusions closed, analysis scheduled for the end of the follow-up period | NCT03296397 |
| SY-DOXY | Nicolas DUPIN | AP-HP | A Randomized Non-Inferiority Clinical Trial of Doxycyline Vs BPG for Early Syphilis | PHRC National 2018 | Completed. Analysis in progress | NCT04838717 | |
| SEM-CORTICO | Saskia ORO | Olivier CHOSIDOW / CDP | ASSISTANCE PUBLIQUE AP-HP | Severe erythema multiforme: randomized controlled trial comparing short systemic corticosteroid therapy vs. placebo during acute phase | PHRC National 2019 | Waiting for inclusion to start | - |
| VAC-WARTS | Johan CHANAL | Olivier CHOSIDOW / GrIDIST, CDP | AP-HP | Nonavalent HPV Vaccine in the Treatment of Difficult-to-treat Palmo-plantar Warts (VAC-WARTS) | PHRC National 2019 | Recruiting | NCT04814446 |
| MADULO | Hélène AUBERT | Sébastien BARBAROT / GREAT, CDP | Nantes University Hospital | Dupilumab step-down strategy to maintain remission in adult and adolescents patients with atopic dermatitis: a non-inferiority randomized trial | PHRC National 2021 | Inclusions closed, analysis scheduled for the end of the follow-up period | NCT05642208 |
| ETHNIC | Thierry PASSERON | Olivier CHOSIDOW / DEFI, CDP | Nice University Hospital | Randomized controlled trial for moderate acne in people with dark skin phototypes comparing early introduction of oral isotretinoin vs. classical strategy | PHRC National 2022 | Recruiting | NCT06447480 |
| BOOSTERS | Bruno MATARD | Olivier CHOSIDOW / CDP | AP-HP | Use of biologics in folliculitis decalvans | PHRC National 2022 | Currently being set up | - |
| PRESENT | Loïc VAILLANT | Olivier CHOSIDOW / GrIDIST, CDP | Tours University Hospital | Prevention of recurrent leg erysipelas: Compression therapy vs. antibiotics | PHRC National 2022 | Pending regulatory approval. Scheduled to be set up in April 2026. | - |
| AFTER | Guillaume CHABY | Olivier CHOSIDOW / DEFI, CDP | AP-HP | Treatment for acne in adult women - Efficacy of low-dose isotretinoin versus spironolactone in the initial phase and spironolactone in the maintenance phase: A 2-step randomized controlled trial | PHRC National 2023 | Waiting for regulatory approvals | - |
| LEISURE | François CHASSET | Olivier CHOSIDOW / DEFI, EMSED, CDP | AP-HP | Lenalidomide vs. methotrexate in difficult-to-treat cutaneous lupus: a randomized controlled trial | PHRC National 2023 | It is scheduled to be set up in April 2026, with recruitment beginning in May. | - |
| BOLERO | Mahtab SAMIMI | GEMUB, CDP | CHU DE TOURS | Efficacy and safety of baricitinib associated with topical corticosteroids in adult patients with difficult-to-treat oral lichen planus: a randomised, double-blind, placebo-controlled trial | PHRC National 2024 | Funding granted, protocol under review following jury selection | |
| OPTIMAD | Sébastien BARBAROT | CDP, GREAT | CHU DE NANTES | OPtimal Therapeutic Intervention for Management of moderate-to-severe Atopic Dermatitis: a multi-arm randomized clinical trial | PHRC National 2024 | Funding granted, protocol under review following jury selection | |
| TINEA TINEA | Sophie LEDUCQ | SFDP, GrIDIST, CDP | CHU DE TOURS | High-dose versus standard-dose terbinafine for tinea in children | PHRC National 2024 | Funding granted, protocol under review following jury selection |